The potency of Streptococcus oralis species of bacteria in the mitigation of two mycotoxins (aflatoxins and ochratoxins) was investigated in this study. Aflatoxins and ochratoxins are a group of secondary metabolites produced in food and feed by two genera: Penicillium and Aspergillus. The fungal spores were cultured on potatoes dextrose agar (PDA) and the colonies so formed were sub cultured on yeast extract agar after which the matured fungal mycelium along with the media was harvested and subjected to extraction using dichloromethane (DCM) to obtain the mycotoxins (aflatoxins and ochratoxins) as secondary metabolite. The sample extract was subjected to Thin Layer Chromatography (TLC) and the plate (chromatograph) was viewed under Ultraviolet source in a UV-hood. The isolated non-pathogenic strain of gram positive Streptococcus oralis specie was tested for its aflatoxin and ochratoxin degradation capabilities. The strain was cultured on a yeast extract agar media separately contaminated with aflatoxins and ochratoxins obtained from the respective toxigenic fungal strains. Extract from these cultures, after two weeks incubation was subjected to thin layer chromatography for qualitative assessment for the presence or otherwise of the two toxins under consideration. While no fluorescence/emission was observed in the case of extract from aflatoxin contaminated dishes, very faint fluorescence was recorded from the ochratoxin contaminated dishes. The study demonstrated that non-pathogenic strain of Streptococcus oralis species has strong and partial potency to biodegrade aflatoxin and ochratoxins respectively.